Frankel Innovation Initiative

The Frankel Innovation Initiative is a $20 million fund supporting the research and development of life-saving therapies and innovative new technologies at Michigan Medicine, with the ultimate goal of improving healthcare and saving lives.

Made possible by a generous donation from the Maxine and Stuart Frankel Foundation, the program seeks to advance innovative research by U-M faculty and provide a fast path to patient impact. It builds on the best practices of the standout programs developed at U-M and other top institutions and capitalizes on U-M’s extensive biomedical research enterprise. Collaborative projects that engage nationally renowned Co-PIs at other institutions are especially encouraged. FFMI is administering the fund.

Open to innovators at all stages of a research project, the Frankel Innovation Initiative offers:

  • $250,000 – $500,000/year to high-impact research projects originating at U-M, with potential for multiple years of support
  • Expertise and guidance from an Advisory Committee consisting of world-renowned scientists and technology development professionals
  • No cost share requirement

Letters of Intent are evaluated on the basis of eligibility and fund appropriateness. After Letters of Intent are reviewed by a triage committee, a select group of faculty will be invited to submit a full proposal for review by the Scientific Advisory Committee for funding consideration.

Watch a Q&A Session about the Frankel Innovation Initiative
Watch Michigan Medicine's The Wrap podcast highlighting the Frankel Innovation Initiative

2021 Awardees

FFMI recently awarded $3 million in funding to six biomedical research projects in the second round of the Frankel Innovation Initiative. The winning projects are:

Investigator Co-Applicant(s) Vertical Proposal Title
Paul Cederna, M.D.
U-M – Surgery		 Cynthia Chestek, Ph.D.
U-M – Biomedical Engineering		 Device Bringing Regenerative Peripheral Nerve Interfaces for Prosthetic Hand Control Home
CLICK HERE to listen to Dr. Cederna on WJR radio.
David Humes, M.D.
U-M – Nephrology		 Stuart Goldstein, M.D., FAAP, FNKF
Cincinnati Children’s Hospital – Nephrology		 Device Immunomodulatory Device to Treat Pediatric Patients with Severe Sepsis and/or Multiorgan Failure
Aditya S. Pandey, M.D.
U-M – Neurosurgery		 Albert Shih, Ph.D.
U-M Mechanical Engineering		 Device Miniature Mechanical Thrombectory Device for Removal of High Fibrin Clots in Brain Arteries
Alvaro Rojas-Pena, M.D.
U-M – Surgery		 Robert Bartlett, M.D.
U-M – Surgery		 Device The Frankel Organ Bank
CLICK HERE to listen to Dr. Bartlett on WJR radio.
Ariella Shikanov, Ph.D.
U-M – Biomedical Engineering		 Molly Moravek, M.D., M.P.H., MSCI
U-M – Obstetrics & Gynecology		 Device Immuno-isolating Capsule for Delivery of Cell-based Therapy for Restoration of Ovarian Endocrine Function
CLICK HERE to listen to Dr. Shikanov on WJR radio.
Molly Stout, M.D., MSCI
U-M – Obstetrics & Gynecology		 Methodius Tuuli, M.D., M.P.H., M.B.A.
Brown University – Obstetrics & Gynecology
Peinan Zhao, Ph.D.
Washington University in St. Louis – Obstetrics & Gynecology		 Device Fully Quantitative Elastography to Predict Preterm Birth

The Frankel Innovation Initiative is designed to build on best practices of the standout programs developed at U-M and other top institutions, and capitalizes on U-M’s extensive biomedical research enterprise as the top public university in research spending in the United States.

SCIENTIFIC ADVISORY COMMITTEE

2020 Frankel Innovation Initiative Winners

Investigator Co-Applicant(s) Vertical Proposal Title
Paul Cederna, M.D.
U-M – Surgery		 Cynthia Chestek, Ph.D.
U-M – Biomedical Engineering		 Device Bringing Regenerative Peripheral Nerve Interfaces for Prosthetic Hand Control Home
David Humes, M.D.
U-M – Nephrology		 Stuart Goldstein, M.D., FAAP, FNKF
Cincinnati Children’s Hospital – Nephrology		 Device Immunomodulatory Device to Treat Pediatric Patients with Severe Sepsis and/or Multiorgan Failure
Alvaro Rojas-Pena, M.D.
U-M – Surgery		 Robert Bartlett, M.D.
U-M – Surgery		 Device The Frankel Organ Bank
Molly Stout, M.D., MSCI
U-M – Obstetrics & Gynecology		 Methodius Tuuli, M.D., M.P.H., M.B.A.
Indiana University – Obstetrics & Gynecology
Peinan Zhao, Ph.D.
Washington University in St. Louis – Obstetrics & Gynecology		 Device Fully Quantitative Elastography to Predict Preterm Birth

Frequently Asked Questions

What is the process for submission of proposals?

Frankel Innovation Initiative awards are made once a year, with Letters of Intent due in May. Application submission and review will be conducted using the University of Michigan Medical School’s Competition Space. Letters of Intent will be evaluated on the basis of eligibility and fund appropriateness. It is highly recommended to contact Bradley Martin, Ph.D., Director, Fast Forward Medical Innovation, at bradmart@umich.edu or 734-936-8577, to discuss your project before submission.

What kind of projects will be funded?

The Frankel Innovation Initiative provides a fast path to patient impact through resources that support life-saving therapies at Michigan Medicine. Innovations at all stages of a research project are encouraged. The program is open to primary investigators (PIs) at the U-M Medical School, and other investigators outside of U-M on a collaborative basis. Collaborative projects that engage nationally renowned Co-PIs at other institutions are especially encouraged to apply.

What will budgets for selected projects be like?

Project budgets depend on the scope of work and technology. Funds dispersed depend on achievement of prospectively agreed upon milestones, which are project specific. Funding will range from $250k-$500k per year, with the potential for multiple years of funding. Please note that no indirect costs are associated with this award. Contact Bradley Martin, Ph.D., Director, Fast Forward Medical Innovation, at bradmart@umich.edu or 734-936-8577, for details related to budgets.

What can the funding go toward?

Allowable budget expenditures include: salary and fringe benefits for project personnel, materials and supplies, contracted research (if required), travel and other relevant costs directly related to advancing the project (to be discussed with Frankel Innovation Initiative staff on a case-by-case basis). Budgets should be primarily allocated to the conduct of research and achievement of milestones. Proposals will be partially evaluated on the appropriateness of project budget.

Who will determine what projects are funded?

The Frankel Innovation Initiative Scientific Advisory Committee comprises global biotech business experts as well as internationally prominent scientists who have deep expert knowledge. The review process consists of multiple steps. A review team, including representatives from the FII Scientific Advisory Committee, performs an initial review of Letters of Intent, selecting projects to submit a full proposal. Full proposals are then reviewed by the full FII Scientific Advisory Committee, who select those that have significant clinical potential for an in-person presentation. Projects which are not selected for further review are provided with feedback. The selected project teams then present their project directly to the FII Scientific Advisory Committee at the committee’s annual meeting in Ann Arbor in September, and awards are granted shortly thereafter.

What further role will the Frankel Innovation Initiative Oversight Committee play?

In addition to reviewing and selecting proposal awards, members of the FII Scientific Advisory Committee and their colleague networks serve in an informal mentorship role to research teams as their projects progress.

QUESTIONS?

Have questions about the Frankel Innovation Initiative? Contact Bradley Martin, Ph.D., Director, Fast Forward Medical Innovation, at bradmart@umich.edu or 734-936-8577.

IDEA CONSULTATION

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